If you've been struggling with severe erectile dysfunction (ED), you may have tried various treatments with limited success. While medications like Viagra or Cialis work well for some men, they don’t provide the desired results for everyone. Fortunately, there’s an alternative: TriMix. This treatment has proven highly effective, especially for men who haven’t responded well to oral medications. At Genesis Lifestyle Medicine, we offer TriMix injections as a safe and powerful option to help you regain confidence and sexual health.

What is TriMix?

TriMix is a compounded medication that combines three powerful drugs—papaverine, phentolamine, and prostaglandin E1—to treat erectile dysfunction. Each of these medications works together to enhance blood flow into the penis, making it easier to achieve and maintain an erection. TriMix is injected directly into the penis, allowing for a more localized effect than oral medications, which can lead to higher effectiveness for some men.

What do each of the medications in TriMix do?

Papaverine

Papaverine is a vasodilator, meaning it helps relax blood vessels and smooth muscle tissue in the penis. By widening these vessels, papaverine increases blood flow, which is essential for achieving an erection. It directly impacts the corpus cavernosum, the spongy tissue that fills with blood during arousal. This enhances the likelihood of a strong, sustained erection.

Phentolamine

Phentolamine blocks alpha-adrenergic receptors, which helps prevent the blood vessels from constricting. In men with erectile dysfunction, certain nerve signals can cause blood vessels in the penis to tighten, restricting the blood flow needed for an erection. Phentolamine counters this by keeping the vessels open, allowing blood to flow more freely.

Prostaglandin E1

Prostaglandin E1, also known as alprostadil, is a natural substance that widens blood vessels and promotes smooth muscle relaxation. It works directly within the penis to encourage blood flow into the erectile tissue. Prostaglandin E1 has been FDA-approved for ED treatment since 1995, and its inclusion makes this combination of drugs particularly effective.
How does TriMix compare to ED medications?

TriMix injections

TriMix injections offer a localized solution to ED, delivering medication directly where it’s needed most. This allows for faster results and often leads to better outcomes for men with severe ED. With TriMix, you have control over the dosage, which can be adjusted to suit your needs over time. While the idea of injecting the penis may seem intimidating, about 70% of men are highly satisfied with their results. Injections typically begin to work within 5-15 minutes.

ED medications

Oral ED medications like Viagra, Cialis, and Levitra are well-known and widely used. They work by increasing blood flow to the penis but require sexual stimulation to be effective. However, not every man responds well to these medications. Some men experience side effects such as headaches, dizziness, or digestive issues, while others find that the pills don’t work for them. In cases of severe ED, oral medications may not provide the necessary level of effectiveness.

Benefits of TriMix injections:

• High success rate: TriMix is particularly effective for men who haven’t responded to oral ED medications, offering a solution for severe or treatment-resistant cases.
• Rapid onset: Injections work within 5 to 15 minutes, giving you greater spontaneity and reducing the need to plan sexual activity hours in advance.
• Adjustable dosage: You can tailor your dose to meet your needs. Genesis Lifestyle Medicine helps determine the right starting dose, and you can adjust it under professional guidance.
• Long-lasting results: Many men experience erections that last long enough for sexual activity, typically around 30 minutes to an hour.
• Minimal systemic side effects: Because TriMix is injected directly into the penis, it has fewer systemic side effects compared to oral medications that circulate through the entire body.

How to inject TriMix for optimal effectiveness:

• Tear open an alcohol swab and clean the bottle’s rubber stopper
• Draw the correct amount of medication into the syringe
• Hold the penis taut and select an injection site away from visible veins
• Insert the needle at a 90-degree angle into the base of the penis
• Inject the medication slowly, then remove the needle and apply pressure for 2-3 minutes

Reclaim optimal sexual vitality with TriMix

TriMix injections offer a powerful and effective solution for men suffering from severe erectile dysfunction, especially when oral medications haven’t worked. By combining three potent medications—papaverine, phentolamine, and prostaglandin E1—TriMix enhances blood flow to the penis, helping you achieve and maintain an erection. At Genesis Lifestyle Medicine, we offer guidance on proper injection techniques and personalized dosing to ensure optimal results.

If you’re ready to explore TriMix injections as a viable treatment for ED, contact Genesis Lifestyle Medicine to explore your options today.