Medications like Semaglutide and Tirzepatide, also known as GLP-1 (glucagon-like peptide-1) agonists, have gained widespread popularity for their effects on weight loss and blood sugar control. They work by mimicking the action of the GLP-1 hormone, which regulates blood sugar levels, suppresses appetite, and promotes a feeling of fullness, making it easier to reduce calorie intake. While their benefits in managing weight and type 2 diabetes are well-known, there’s a concern that comes with significant weight loss: muscle loss.

When you lose weight quickly, as can happen with GLP-1 agonists, there’s a risk that your body may break down muscle tissue alongside fat. Muscle loss can impact your metabolism, strength, and overall vitality, especially as you age. However, with the right strategies, it’s possible to retain and even build muscle mass while benefiting from the weight loss effects of GLP-1 medications. In this article from Genesis Lifestyle Medicine, we will explore several effective methods to maintain your muscles while on GLP-1 therapy.

Engage in resistance training to stimulate muscle growth

One of the most powerful ways to preserve muscle mass while on GLP-1s is through resistance training. When you lift weights or perform body-weight exercises, your muscles undergo stress and tiny tears. As these tears heal, your muscle fibers grow back stronger and larger. This is crucial while losing weight, as it prevents your body from turning to muscle as a fuel source.

Incorporating compound exercises that target major muscle groups can be especially effective. Squats, deadlifts, bench presses, and rows are excellent choices for building and maintaining muscle. If you’re new to resistance training, simple body-weight exercises like squats, push-ups, and even lifting household items like gallons of water can give your muscles the workout they need. Aim for at least two to three strength-training sessions per week.

Prioritize protein intake to support muscle repair

Diet plays a critical role in retaining muscle mass, particularly when you’re on GLP-1s. Protein is the building block of muscle, and consuming enough of it is essential for muscle repair and growth. Without sufficient protein, your body may not have the resources to maintain muscle tissue, which can lead to muscle loss over time.

Aim to include high-quality protein sources in each of your meals. Lean meats, poultry, fish, eggs, and dairy are excellent options, but plant-based proteins like nuts, seeds, and legumes can also contribute to your daily intake. If you struggle to get enough protein through whole foods, consider adding a protein shake to your routine. To support muscle retention and growth while on GLP-1s, aim for at least 0.8 to 1 gram of protein per pound of body weight.

Stay active to keep your body in motion

While resistance training is essential for muscle growth, staying active in other ways can further support muscle retention. Activities like walking, swimming, cycling, and even yoga help keep your body moving and maintain muscle function. Regular movement stimulates blood flow to your muscles and helps prevent the loss of muscle mass that can occur with inactivity.

Make it a point to engage in some form of physical activity every day. Even if it’s just a 30-minute walk or a quick stretching routine, staying active will help maintain your muscle mass and keep you feeling energized. Over time, these activities will complement your strength-training efforts, making it easier to retain muscle while you lose weight.

Stay hydrated for optimal muscle function

Proper hydration is often overlooked but is vital for maintaining muscle health. Water plays a crucial role in muscle function, helping transport nutrients to your muscle tissues and removing waste products. When you're dehydrated, your muscles may not function as efficiently, which can lead to fatigue and muscle breakdown over time.

Make sure you're drinking enough water throughout the day, especially if you're exercising regularly. A general guideline is to aim for at least 8-10 cups of water daily, but you may need more if you’re engaging in physical activity or live in a hot climate. Staying hydrated will support your muscles, keep your energy levels up, and contribute to overall well-being.

Try non-invasive body contouring treatments like EMSCULPT NEO

In addition to lifestyle changes like exercise and diet, non-invasive body contouring treatments can further support muscle retention. One cutting-edge option is EMSCULPT NEO, a treatment available at Genesis Lifestyle Medicine. EMSCULPT NEO uses high-intensity electromagnetic energy to induce muscle contractions that are much stronger than what you could achieve through regular exercise. This helps build muscle while simultaneously reducing fat.

Each session of EMSCULPT NEO typically lasts about 30 minutes, during which the machine stimulates thousands of muscle contractions. This not only helps you retain muscle mass but can also improve muscle tone and definition, making it easier to achieve a leaner, more sculpted appearance as you lose weight. Best of all, it’s non-invasive, meaning there’s no downtime, and you can continue with your regular routine immediately after treatment.

Maintaining muscle mass while losing weight on GLP-1 medications like Semaglutide and Tirzepatide is essential for preserving your metabolism, strength, and vitality. Contact Genesis Lifestyle Medicine they are here to support you with personalized guidance and treatments to help you maintain muscle mass and optimize your health throughout your weight loss journey.