You’ve taken the leap and started using Semaglutide for weight loss. The results are promising—those numbers on the scale are dropping, and you’re feeling hopeful about your weight and health. Semaglutide helps control your appetite and makes it easier to maintain a calorie deficit, bringing you closer to your goals. But then, a less pleasant side effect appears: diarrhea.

At Genesis Lifestyle Medicine, we understand that side effects like diarrhea can be frustrating, but they don’t have to derail your journey. With some practical steps and adjustments, you can minimize the impact of diarrhea while staying on track with your weight loss goals. Here are some tips to help you manage and reduce this common side effect of Semaglutide.

Increase your intake of soluble fiber

One of the simplest and most effective ways to manage diarrhea is to increase your intake of soluble fiber. Soluble fiber absorbs water and helps bulk up your stools, making them firmer and reducing the urgency and frequency of bowel movements. This type of fiber is particularly beneficial for individuals experiencing diarrhea from Semaglutide, as it can slow down the movement of food through your intestines and allow more time for water to be absorbed.

Foods rich in soluble fiber include oats, beans, lentils, peas, apples, bananas, and sweet potatoes. Adding these to your diet can help stabilize your digestion. Just be careful not to increase your fiber intake too quickly, as adding too much fiber at once can have the opposite effect and actually worsen diarrhea. Start slowly and gradually increase your intake.

Stay hydrated with electrolytes

Diarrhea can lead to dehydration, especially if you are losing a lot of fluids. This can result in weakness, dizziness, and fatigue. It's important to stay hydrated by drinking plenty of water, but when you’re losing both water and minerals, water alone may not be enough.

To combat dehydration, you can use oral rehydration solutions that contain electrolytes like sodium, potassium, and chloride. These electrolytes help replace the minerals lost through diarrhea, ensuring your body stays balanced and hydrated. If you’ve been experiencing both diarrhea and vomiting, rehydration is even more critical.

Avoid high-fat and greasy foods

While you’re on Semaglutide, it’s important to avoid high-fat and greasy foods, as they can exacerbate digestive issues like diarrhea. Semaglutide can alter the way your body digests food, and fatty meals can be harder to process, potentially triggering loose stools. Greasy foods can also move through your digestive system too quickly, increasing the risk of diarrhea.

Instead of fatty, fried, or greasy meals, focus on eating lighter, easier-to-digest foods. Grilled, steamed, or baked options are typically gentler on your digestive system, but they still provide the nutrients you need to support your weight loss goals. Choosing lean proteins, whole grains, and plenty of vegetables can keep your digestion more stable while taking Semaglutide.

Eat smaller, more frequent meals

Large meals can strain your digestive system, making diarrhea worse, especially in the early stages of Semaglutide treatment. To minimize this risk, try eating smaller, more frequent meals throughout the day. This gives your digestive system more time to process and absorb nutrients without becoming overwhelmed, thus reducing the risk or frequency of diarrhea.

Aim to eat balanced meals every three to four hours, ensuring each one contains a mix of protein, healthy fats, and fiber-rich carbohydrates. This helps with diarrhea, stabilizes your blood sugar levels, and reduces the appetite fluctuations that sometimes occur with Semaglutide use.

Use medications to slow digestion

In some cases, lifestyle changes alone might not be enough to resolve diarrhea. If this happens, your provider at Genesis Lifestyle Medicine might recommend an over-the-counter medication like Loperamide. This medication works by slowing down the movement of food through your gut, which allows your body to absorb more water from your stools and make them firmer.

While Loperamide can be very effective, it’s important to follow your provider’s guidance on how and when to use it. It should be taken on a short-term basis and only as directed to avoid potential side effects. Always consult with your healthcare professional before starting any new medication, even over-the-counter options, to ensure it’s the right fit for your situation.

Gradually adjust to the medication

When starting Semaglutide, it’s common to experience digestive side effects like diarrhea. However, these side effects often improve as your body adjusts to the medication. One way to minimize the severity of diarrhea is to start with a lower dose of Semaglutide and gradually increase it under the guidance of your healthcare provider. This gives your body more time to adapt and can reduce the initial gastrointestinal discomfort that many patients experience.

At Genesis Lifestyle Medicine, your provider will work with you to create a dosage plan that considers your unique health needs and weight loss goals. By adjusting your dosage, you can minimize unpleasant side effects and stay on track with your weight loss progress.

Managing diarrhea while taking Semaglutide doesn’t have to interfere with your weight loss journey. By making smart dietary choices, staying hydrated, eating smaller meals, and using medications or supplements as needed, you can minimize this side effect while continuing to shed excess pounds and focus on the benefits of your treatment. Contact us today for more information.